Affiliations: Centre for Genomic and Experimental Medicine and MRC Human Genetics Unit

I am a postdoctoral research associate in health data science with interested in modelling longitudinal biomarker trajectories and disease outcomes for inflammatory bowel disease. I am in the Lees group in the Centre for Genomic and Experimental Medicine and in the Vallejos group in the MRC Human Genetics Unit.

My research interests include longitudinal modelling, survival analysis, electronic health records, and machine learning.

I am also an R package developer. My packages can be found on GitHub.

In my personal life, I enjoy swimming, the gym, playing bass guitar, and all things technology.


Apr 6, 2023   Longitudinal Fecal Calprotectin Profiles Characterize Disease Course Heterogeneity in Crohn’s Disease is now available at Clinical Gastroenterology and Hepatology!

Aug 17, 2022   Latent Crohn’s Disease Subgroups are Identified by Longitudinal Faecal Calprotectin Profiles is available on medRxiv!

Mar 23, 2022  gameR has been released on CRAN!

Feb 19, 2022  This website has gone live!

Nov 5, 2021  datefixR has been released on CRAN!


Real-world experience with tofacitinib in ulcerative colitis: a systematic review and meta-analysis
Laura A. Lucaciu,  Nathan Constantine-Cooke, Nikolas Plevris, Spyros Siakavellas, Lauranne A.A.P. Derikx, Gareth-Rhys Jones, and Charles W. Lees
Therapeutic Advances in Gastroenterology Dec 202
Longitudinal Fecal Calprotectin Profiles Characterize Disease Course Heterogeneity in Crohn’s Disease
Heterogeneity in Crohn’s Disease
Nathan Constantine-Cooke, Karla Monterrubio-Gómez, Nikolas Plevris, Lauranne A.A.P. Derikx, Beatriz Gros, Gareth-Rhys Jones, Riccardo E. Marioni, Charlie W. Lees, and Catalina A. Vallejos
Clinical Gastroenterology and Hepatology Mar 2023